The aim of this paper is to accentuate the importance of interdisciplinary higher education. Interdisciplinary higher education is integrative i.e., knowledge of different disciplines is contrasted and changed by integration which represents its defining characteristic. It develops boundary-crossing skills, an ability to change perspectives, to synthesize knowledge of different disciplines, to cope with complexity, to apply different methodologies in research, and to propose solutions to complex problems. Thus, the ability to integrate knowledge is considered as the most important learning outcome of interdisciplinary higher education called interdisciplinary understanding or interdisciplinary thinking (Spelt et al. 2009). The present paper describes and discusses a specific example of one interdisciplinary undergraduate study program in Business Communication and Translation in English offered at the University American College Skopje, as a case study. The results of the research suggest that although interdisciplinarity in higher education is a challenging task, it is of great importance to implement it properly in order to achieve its aims. Translation and business communication studies are interdisciplinary in their essence. That is why intentional and meaningful interdisciplinary provisions in the translation and business communication study programs are necessary to train skilled translators and business communication professionals. Despite the challenges, the research suggests ways how to put in practice interdisciplinary provisions in higher education.