The chapter establishes the convergence of artificial intelligence, neuroscience, and cybersecurity as an operational necessity, introducing the “Neuro-Agentic Security” paradigm where these three domains intersect to create multiplicative security capabilities. Modern hybrid threats now combine technical exploits with cognitive manipulation such as deepfake-enhanced social engineering, AI-powered behavioral profiling, and adversarial machine learning evolving into multi-dimensional campaigns that target human psychology and decision-making rather than systems alone. These sophisticated attacks exploit cognitive biases, emotional vulnerabilities, and decision fatigue through personalized manipulation that operates below the threshold of traditional detection. Neuroscience provides unprecedented visibility into cognitive states such as stress, deception, and insider intent through EEG, fNIRS, and physiological monitoring. Ethical compliance is framed not as regulatory burden but as foundational to responsible innovation, requiring privacy-bydesign architectures, granular consent mechanisms, and collaboration among technologists, ethicists, and policymakers to ensure neurosecurity capabilities enhance rather than compromise human flourishing.