Network Pharmacology to Clarify the Effective Substances and Their Action Mechanisms of Traditional Chinese Medicines
摘要
Traditional Chinese medicines (TCMs) were applied to treat various biological diseases with a long history. TCMs are characterized by multiple components corresponding to abundant targets and holistic effects in body. The network pharmacology, as a constructive technology integrating multiple sources of information, not only considers the pharmacology response of TCMs in cellular or phenotypic levels, but also reflects the characterization of chemical material basis in TCMs. It is very crucial to fully consider the source of chemical components representing the whole TCM for expanding its network pharmacology research. More persuasive multi-component network pharmacology would be conducive to elucidate the quality control and therapeutic mechanism of TCMs.