Medical Applications of Systems Biology
摘要
The vast figure of described molecular agents connected to pathogenesis could not be integrated easily or handled by traditional analytical procedures due to the exponential growth of highly sophisticated medical and scientific analysis tools over the past 30 years. In fact, the increased number of complicated diseases being defined has, in part, been caused by the recognition that various moieties represent disease markers. Thanks to currently accessible cutting-edge technology, scientists and doctors may now look into and evaluate any particular dysregulations occurring at the genomic, microRNA (miRNA), transcriptome, and protein levels. The fact that just isolated molecular levels are separately examined for its influence on each specific health condition presents a limitation in this scientific brave new world. Later its inception in the 1992 year, systems biology and remedy have mostly focused on the changes in complete route kinetics that lead to the beginning and/or worsening of the condition(s) under investigation. In order to shed light on a variety of study settings, systems medicine methodologies can be used. This has the practical benefit of revealing unique dynamic binding interactions that are crucial for affecting the progression of medical disorders. As a result, systems medicine helps to pinpoint clinically significant drug targets for preventative and curative actions against this illness.