Rectal Gastrointestinal Stromal Tumors with Preoperative Treatment

Generally, GIST occurs in the stomach and small intestine, accounting for 50–60%, and 20–30% of cases, respectively. Primary rectal GIST are relatively rare [1]. When considering treatment for rectal GIST, especially low rectal GIST, whether the anus can be preserved during surgery determines the patient’s postoperative quality of life. Preoperative treatment can reduce the size of the tumor, reduce the clinical stage, and increase the distance between the tumor and the anus. Subsequently, this can allow some patients with low rectal GIST to retain the anus without affecting their overall survival time and improve the postoperative quality of life.