Neurofibromatosis Type 1 Associated Gastrointestinal Stromal Tumors

章节
发表日期：

2024年

查看全文

Yao Lin,
Xiangyu Zeng,
Chengguo Li,
Zhidong Gao,
Jian Li

摘要

Neurofibromatosis type 1 (NF1), or von Recklinghausen disease, is an autosomal dominant genetic disease. Patients with NF1 are prone to develop various types of tumors, including GIST [1]. For patients with NF1, GIST mainly occur in the duodenum and jejunum. Multiple primary tumors and wild-type KIT and PDGFRA are the most significant features [2].