Immune Regulation

Immune regulation is the regulation and control of the immune response by the immune system in order to maintain homeostasis of the organism. Once started, the immune response is like an accelerating train that must be braked to keep it running smoothly and eventually come to a stop. In the whole process of immune response, immune regulation plays the role of braking, which is accomplished through immune regulatory cells, so the main body of immune regulation is immune regulatory cells. By regulating the direction and intensity of the immune response, immune regulatory cells orient the immune response towards cellular immunity or humoral immunity and keep it in the most appropriate state of physiological response, thus maintaining the physiological balance and stability of the body. However, if the immune regulation is out of control, it can cause the body to have abnormally excessive immune response, leading to immune damage or even death by shock. Therefore, immune regulation determines to some extent the physiological state and immune tolerance of animals, especially in the adaptive immune response where immune regulation plays a key role.