Gut Microbiome and Brain Aging
摘要
The concept that the gut microbiota plays a significant role in maintaining physiological status in the gastrointestinal (GI) system is supported by both qualitative and quantitative transformation of the intestinal flora in various physiological and pathological conditions, as revealed in various research studies. A relationship between the gastrointestinal system and cognitive functioning is clearly suggested by the evidence of neuroinflammation that is seen in neurodegenerative illnesses like Parkinson’s and Alzheimer’s. Many factors will affect or influence the gut microbiota. Dysbiosis in the gut microbiome is linked to a decreased immune response, which encourages the growth of skin diseases and causes hair-related disturbances. Gut microbiome alteration is related to many skins and hair-related disorders. Gut-brain cross-talk has significantly improved the interaction between gut microbiota and gut hormones. Ayurveda can be applied to cosmetics to balance or symbiosis the gut microbial ecology using organic plant botanicals. According to this perspective, a physiological and non-pathological aging process may be facilitated by modulating gut microbiota, which considers the interdependence of microbiota products, inflammation mediators, and the immune system. It may also help to contrast the advancement of degenerative mechanisms. Certain investigations, with encouraging outcomes, have already characterized the gut microbiota of elderly people. The connection between gut microbiota, aging, and the degenerative diseases that plague older people should be better understood through future research.