Brain Abscess

Central nervous system (CNS) infections are difficult to diagnose and manage resulting in high mortality and morbidity due to neurological sequelae like cognitive impairment and seizure disorders. A plethora of organisms including viruses, bacteria, fungi, and parasites may invade the CNS. The antimicrobial choice is limited due to physiological barriers in the CNS. Brain abscesses are focal suppurative lesions caused mainly by bacteria including mycobacteria, fungi, and parasites. The immunocompromised host is more vulnerable. Effective management often includes surgery along with supportive care especially care of the raised intracranial pressure. Antibiotic duration is prolonged, often more than eight weeks, Repeated brain imaging is necessary to ascertain the resolution of the lesion.