Biological Pathway Identification

Genome-wide association study (GWAS) has become an essential method to reveal the genetic mechanism of complex diseases. In the past decade, the research on GWAS methods has gradually advanced from the initial single-locus, single-trait analysis to multi-locus, multi-trait association analysis, but the results can only explain a small portion of the genetic power. Therefore, the methodological study of GWAS is of great importance.