People with multiple chronic conditions tend to have poor health, increased use of healthcare services, and lower quality of life. The aim of this chapter is to examine the pattern of healthcare utilization and out-of-pocket expenditure (OOPE) of chronic diseases among older adults in India. A total of 72,250 respondents from the first wave of Longitudinal Ageing Study in India (LASI) conducted in 2017–18 was used for analysis. The mean number of days of hospitalization and OOPE by chronic diseases was estimated across the socioeconomic group. Further, the binary logistic regression analysis was used to understand the association of hospitalization (during last 365 days) and outpatient visit (during last 30 days’ visit) across the socioeconomic group. In India, 7.1% older adults aged 45+ were hospitalized during last 365 days and 28.3% sought outpatient care during 30 days’ reference period. About 4.1% older adults were hospitalized without any chronic condition, 8.4% with one chronic disease, 11.9% with two chronic diseases, and 17.8% with three and more chronic diseases. Similarly, among those without any chronic conditions, 24% sought outpatient visit compared to 31.1% with single chronic disease and 35.9% with multiple chronic diseases. The OOPE on hospitalization without chronic disease was ₹15,843, ₹21,681 with one chronic disease, and ₹55,899 with multiple chronic diseases. The odds of hospitalization and seeking outpatient service with multiple chronic conditions were 5.05 (95% CI, 4.58–5.58) and 2.63 (95% CI, 2.45–2.81), respectively, as compared to those without any chronic condition. Increasing number of chronic diseases among older adults was associated with a significant increase in utilization of healthcare services and high OOPE. Healthcare protection is recommended for well-being of older adults in India.