Numerical Study on the Effect of Exercise on Various Configurations of Stenosis in Coronary Artery

One of the primary factors in adult fatalities is coronary artery disease. Hence, the study on the effect of stenosis position and number of stenoses becomes necessary to predict the susceptibility of formation of another stenosis and predict atherosclerotic plaque rupture. The probability of plaque rupture increases under exertion; hence, the current study uses two different pulse rates (75 BPM for the rest condition and 120 BPM for the exercise condition). Higher time-averaged wall shear stress (TAWSS) values are observed in case of double stenoses even at rest conditions. A substantial increase in peak TAWSS value is observed under exercise conditions compared to rest conditions. A downstream shift in oscillatory shear index (OSI) region is observed under exercise conditions for all cases, whereas a significant reduction in OSI region is observed in the case of proximal stenosis.