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Effect of Viscosity on the Margination of White Blood Cells in an Inertial Flow Microfluidic Channel

  • Dhiren Mohapatra,
  • Rahul Purwar,
  • Amit Agrawal

摘要

White Blood Cells (WBCs) play a significant role in defending and eliminating infection-causing external elements and are indicators of several diseases, such as inflammatory diseases, cancer, and allergies. Here, microfluidic devices have an upper edge in the accurate and fast processing of the sample, which is needed for speedy disease prediction. In specific, passive microdevices are valuable as they are simple, cheap, and effective compared to the current inefficient conventional methods. Here we have analysed the effect of viscosity on the margination of WBCs in inertial flow in a rectangular channel with a bifurcation. We added known concentrations of viscoelastic fluid to vary the viscosity of the sample. WBC margination was analysed from the values of WBC enrichment with respect to viscosities.