Metabolites from Fungi: A Promising Source of Lead Compounds Against Cancer
摘要
The diversity of fungi represents a fabulous and remarkable asset of sources of bioactive compounds with vast potential for pharmaceutical applications. Especially in Oncology, there is a relentless search for new drugs that allow for more effective and long-lasting treatments with fewer side effects. Innovations in fungi isolation, cultivation, genetic engineering, and metabolic extraction techniques have raised the probability of obtaining fungal metabolites and their derivatives from the most diverse ecosystems worldwide. We review the recent studies on antineoplastic compounds originating from fungal secondary metabolites, which can provide essential alternatives to reinforce the arsenal of chemotherapeutic agents to fight cancer.