Toxicity Issues of Nanoparticles in the Delivery of Phytoconstituents and Cosmeceuticals

Science of combining active pharmaceutical ingredients with the cosmetics for the purpose of therapeutic effects in addition to beautifying, cleansing, coloring, and other beneficial effects are growing nowadays very rapidly. As combining active pharmaceutical ingredients (API) and active phytoconstituents are becoming beneficial for the consumers and the manufacturers both, but due to some limitation like poor stability, poor skin permeability, low solubility, and less availability to the targeted region of the body parts of the active ingredients were hindering the formulation of efficient cosmeceutical products. But the emergence of nanotechnology era became the excellent fortune to the cosmetic companies to reduce these drawbacks issues by combining the nanocarriers with the API and phytoconstituents of cosmetics, known as nanocosmeceuticals. Nanocosmeceuticals’ concept improved the stability, skin penetration capability, targeted drug delivery, and long-term impacts of active ingredients of cosmeceutical products. Despite of these advantages of the nanosystems implications in the cosmeceutical products, concerns about toxicity issues to the consumers and harmful effects on environment are also raising as still there are no implicated safety regulation by the governments. Hence, manufacturers should keep in mind about safety and perform clinical trials of the nano-based cosmeceutical products and should label the nano-materials used to avoid any hazardous health effects.