Synthesis, Characterization and Various in Vitro Activities of Essential Oil-Loaded Polymeric Nanoformulations

The main objectives of the present research were to synthesize cumin essential oil-loaded polymeric nanoformulations using the ionic gelation method and use it in a variety of in vitro activities. Cumminium cyminum is well known in world among the spices and if we discussed its seeds that also contain good amount of oil content having various bioactive compounds like cumin aldehyde, P-cymene, D-limonene, terpinene and eugenol with considerable potential in various in vitro activities. Various techniques were used to characterize the synthesized nanoformulations. Using a particle size analyzer, the nanoformulations obtained had diameters ranging from 20 to 400 nm. The nanoformulations could be aggregated with a nearly spherical shape, as seen by SEM analysis. The nanoformulations, cumin oil and ascorbic acid exhibit strong antioxidant activity, ranging from 27 to 80% as assessed by the DPPH assay.