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Molecular Biomarkers of Cancer and Their Diagnostic Applications

  • Aitizaz Ul Ahsan,
  • Sweety Mehra,
  • Ranbir Chander Sobti,
  • Mani Chopra

摘要

Cancer, characterized by abnormal cell growth, remains a significant global health concern. The intricate interplay of genetic, epigenetic, and proteomic components is intricately linked to cancer progression and persistence. Molecular biology research in the field of cancer is rapidly advancing, leading to fruitful investigations in cancer diagnosis, prognosis, and monitoring. Molecular cancer biomarkers have emerged as crucial elements in cancer biology, with their discovery and implications revolutionizing the field. However, the successful translation of this wealth of information into effective cancer monitoring and treatment poses a major challenge. This chapter provides a comprehensive overview of the diverse types of cancer biomarkers, highlighting recent advancements, addressing associated challenges, and discussing the clinical implications of molecular cancer biomarkers. By delving into these topics, this chapter aims to enhance our understanding of the potential of molecular biomarkers in advancing cancer management strategies.Nowadays, abnormal cell growth also known as cancer is a major global concern. The functional intricacy of genetic, epigenetic, and proteomic components has been associated with the progression and persistence of particular cancer. Molecular biology dealing with cancer is advancing with the progression of cancer, and new investigations are fruitful in the diagnosis, prognosis, and monitoring of cancer. The discovery and implications of molecular cancer biomarkers play a vital role in cancer biology. Over time, novel cancer biomarkers are being developed on the basis of cancer type, but the major challenge is the translation of achieved information in successful monitoring and curing of cancer. Therefore, this chapter will summarize the various types of cancer biomarkers, advancements, challenges, and clinical implications of molecular cancer biomarkers.