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A general introduction of sea buckthorn phenolics is summarized, highlighting their various bioactivities including antioxidant, antimicrobial, anti-inflammatory, anti-cancer, cardiovascular protective, and hypoglycemic effects. Additionally, the mechanisms underlying the anti-cancer properties of sea buckthorn phenolics, particularly their regulation of the cell cycle, apoptosis pathways, and the PI3K/Akt/mTOR pathway in human breast cancer cells, are discussed both in vitro and in vivo.

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Bioactivities of Sea Buckthorn Phenolics and Their Anti-cancer Mechanism Toward Human Breast Cancer Cells

  • 章节

  • 发表日期：

    2025年

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  • Xiaobo Wei,
  • Yaoran Li,
  • Peiyi Zhu,
  • Jinhu Tian

摘要

A general introduction of sea buckthorn phenolics is summarized, highlighting their various bioactivities including antioxidant, antimicrobial, anti-inflammatory, anti-cancer, cardiovascular protective, and hypoglycemic effects. Additionally, the mechanisms underlying the anti-cancer properties of sea buckthorn phenolics, particularly their regulation of the cell cycle, apoptosis pathways, and the PI3K/Akt/mTOR pathway in human breast cancer cells, are discussed both in vitro and in vivo.