Nickel base deformed superalloy is a new generation of combustors material in China, In this paper, tensile fatigue properties of test samples were tested at 200 °C, 550 °C and 900 °C. The corresponding stress of fatigue cycle in the range of 5 ~ 300 times at each temperature was measured, At the same time, the microstructure of the material failure fracture was observed and analyzed. in order to establish a numerical simulation technology suitable for the tensile fatigue performance of Nickel base deformed superalloy material, the stress distribution of the sample under fatigue load was simulated by using ABAQUS finite element analysis software in this paper, then based on the nominal stress method of Fe-safe fatigue analysis software, the fatigue life of the sample is calculated. The results show that the simulation results of the sample are consistent with the fatigue test results. Based on this method, the thin-wall bearing structure of flame tube is simulated, and the fatigue life of flame tube under service load is simulated.