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In this era of technological advancement, the role of nanoparticles (NP) is vast, mainly due to their enriched performance and pliable characteristics. In this chapter, we will be learning about the various types of cellular uptake of nanoparticles and their interactions with cell and extracellular matrix. These interactions are crucial for internalizing NPs into cells and extracellular matrix. This chapter reviews the different types and mechanisms of NP uptake and their properties and discusses factors influencing nanoparticles and cellular interactions. We also mentioned various quantification techniques, highlighting the role of flow cytometry in analyzing nanoparticle uptake and localization. The insights provided aim to enhance NP-based applications in various fields like drug delivery, imaging, and diagnostics.

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Flowcytometric Capturing of Nanoparticles Internalization in the Cell System

  • 章节

  • 发表日期：

    2025年

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  • Ragavi Ravindran,
  • Srividhya Nandagopal,
  • Muthu Kumaran Panneerselvam,
  • Kamla Kant Shukla

摘要

In this era of technological advancement, the role of nanoparticles (NP) is vast, mainly due to their enriched performance and pliable characteristics. In this chapter, we will be learning about the various types of cellular uptake of nanoparticles and their interactions with cell and extracellular matrix. These interactions are crucial for internalizing NPs into cells and extracellular matrix. This chapter reviews the different types and mechanisms of NP uptake and their properties and discusses factors influencing nanoparticles and cellular interactions. We also mentioned various quantification techniques, highlighting the role of flow cytometry in analyzing nanoparticle uptake and localization. The insights provided aim to enhance NP-based applications in various fields like drug delivery, imaging, and diagnostics.