Large amounts of food are wasted every year, with significant environmental, social, and economic impacts. All these perspectives are presented in the first part of the book chapter. Food waste from different sources contains a variety of substances that can be transformed into numerous value-added products, which are summarized in the next part of the chapter, with an emphasis on those products with potential nutraceutical applications. The increasing demand for safe and effective nutraceuticals is driving the need for sustainable approaches to their production and development. Current approaches to convert food waste into value-added products for nutraceuticals are highlighted in the main parts of the chapter, with a focus on improving the economic and environmental sustainability of the processes together with the safety, stability, and efficacy of the products. The final part of the chapter discusses the limitations of current approaches and future perspectives on the valorization of food waste for nutraceuticals.