It is necessary to carry out effective traffic organization optimization design of the connecting section of urban expressway off-ramp and its downstream intersection in order to avoid the adverse impact on the capacity and safety of connecting section caused by weaving movements. This paper summarizes the traffic organization optimization method of the connecting section, introduces an improved Webster timing signal timing algorithm, and proposes a combination optimization scheme of signal timing and traffic organization according to the conditions. The evaluation index system considering the traffic ability and safety of the connecting section and the intersection is established, and the comprehensive evaluation model is constructed by using the matter-element analysis method. VISSIM is used to simulate and analyze the combination optimization scheme for a typical case and its field survey data. The simulation result is evaluated by the comprehensive evaluation model. The simulation results show that the optimization method can optimize the connecting section and intersection in a number of evaluation indicators, and improve the traffic operation.