With the rapid development of global trade, multimodal transport as an efficient mode of transport, its importance in the field of logistics has become increasingly prominent. However, the traditional multimodal transport mode has information island, low efficiency of document circulation, high trust cost and imperfect coordination mechanism, which leads to the problem of difficult coordination between entities in the implementation process of “one single system”. This paper aims to explore how to use blockchain technology to build a new type of “one single system” mode of multimodal transport. Combining with emerging technologies such as cloud computing, big data and artificial intelligence, it proposes the construction strategy of “one single system” of multimodal transport in China. By constructing the data framework of “one single system” of multimodal transport online and implementing the “one single system” of multimodal transport online step by step, logistics efficiency is improved. Reduce operating costs and increase transparency and safety in the transportation process.