The serial communication protocols include the Universal Asynchronous Receiver Transmitter (UART) standard. It is an integrated circuit that is used to asynchronously transmit and receive data over the computer’s serial port. Bytes of data are taken and transmitted by the UART as sequential bits. The second UART resembles the bit into whole bytes at the destination. UART is primarily used to transmit data cheaply, quickly, and over small distances among two embedded devices. This article’s primary focus is on the UART implementation for RFID modules with various FPGA technologies. Transmitter, Receiver, and Baud Rate Generator are the three main components of the design. UART protocol is now frequently used by RF-Microcontroller modules to connect to other electronics. On many FPGAs, a simplified Finite State Machine (FSM) UART design has been put into practice. The design is made more stable and dependable using FSM. With its RF components, UART offers extremely reliable long-distance transmission. Verilog HDL is utilized to implement the suggested design, and Xilinx ISE 12.1, 14.7, Xilinx Vivado 2018 and Intel Quartus Prime 19.1 are used for simulation. These FPGAs are used to determine the highest speed that may be achieved and the associated power consumption.