High Efficiency and power quality can be achieved using multilevel inverters for medium-voltage and high-power applications. The cascaded H-bridge multilevel inverter topology with asymmetric voltage sources generates high-resolution output using an optimum number of switches. The nearest space vector control is one of the prominent modulation methods used for high-resolution multilevel inverters because of their simplicity and low computation requirements. For a given reference in the space vector, the device switching frequency can be minimized by selecting a specific switching sequence from multiple possibilities for a given space vector point. Emphasis is placed on minimizing switching during sector transitions through the use of a look-up table, investigating its impact on power distribution ratios in the 4:1 asymmetric multilevel inverter configuration. This reduction in the number of switching reduces the power handled by the auxiliary converters and at the same time, it reduces the switching and conduction losses also. From the findings can be inferred that a lower bidirectional supply requirement VA rating is required for the converter operation in the regeneration region. The simulation performed in MATLAB/Simulink matches well with the experimental results.