The open-end winding (OEW) dual-inverter are widely used in various industrial applications, especially in critical areas where fault-tolerant control (FTC) is usually required to ensure continuous operation of the inverter under fault conditions. In this paper, a fault-tolerant topology of open-winding dual three-level active neutral point clamped (3L-ANPC) inverter is proposed, which connects the load to the neutral point of the corresponding capacitor through additional switches, and can realize the FTC of various single-phase fault. In addition, this paper derives a unified expression of the carrier-based pulse width modulation (CBPWM) with zero-sequence component injection for FTC of single-phase faults in three-level inverter, which eliminates the procedure for determining the sectors and calculating the dwell times of vectors, and greatly alleviate the computation burden of space vector PWM (SVPWM). Finally, the simulation results validate the effectiveness of the FTC strategy.