Under the background of “carbon peaking and carbon neutrality”, low-carbon policies and technical measures provide a new path for the realization of energy saving, emission reduction and energy recycling in the integrated energy system. As a key link in energy conversion and energy coupling, power to gas bears an important task of low carbon emissions. Based on this point, this thesis first refines the operation process of power to gas into two stages called power to hydrogen and hydrogen to gas. Secondly, a framework for the coordinated operation of power to gas and gas hydrogen doping based on the hydrogen energy flow is constructed. Finally, an optimal model of mixed integer linear programming (MILP) is established to minimize the day-ahead operating cost. After being solved by Cplex solver, the optimal operation plan of the system can be obtained.