Organ Correlation and Antiaging Medicine: Gut-Brain Correlation and Antiaging

The functional relationship between the central nervous system and the digestive tract is called the brain-gut interaction [1]. The functional relationship between the central nervous system and the digestive tract can be broadly divided into (1) signals from the central nervous system to the digestive tract, and (2) signals from the digestive tract to the central nervous system (Fig. 53.1). The brain-gut interaction assumes a bidirectional relationship of (1) and (2). On the other hand, when the order of the words “gut” and “brain” is reversed to “gut-brain interaction”, it often implies an emphasis on the (2) signal [2]. When analyzing the effects of intestinal bacteria on the body, the components that intestinal bacteria have on the (2) signal become the main focus.