Functionality of Supplements and Anti-aging: Functionality of Supplements—Neurology

Prevention of lifestyle diseases is a fundamental principle for achieving anti-aging of the brain. In our dementia clinic, 66.6% of 968 Alzheimer’s disease (AD) patients had some form of lifestyle disease, with hypertension (HT) at 54.1%, dyslipidemia (DL) at 28.4%, and diabetes mellitus (DM) at 18.2%. It was found that just under 70% of AD patients have a lifestyle disease [1]. Furthermore, 21.6% of patients had two diseases, and 6.3% had three diseases, indicating that major internal diseases, lifestyle diseases, are highly prevalent in AD patients [2]. Among these 968 AD patients, 570 who could also have their waist circumference measured, 36.7% met the criteria for metabolic syndrome (men ≥85 cm, women ≥90 cm), and of these, 75.6% had some form of lifestyle disease. Among these, 59.8% had HT, 37.3% had DL, and 26.8% had DM, indicating that over 75% of AD patients with metabolic waist circumference have a lifestyle disease. Furthermore, 30.1% of patients had two diseases, and 9.1% had three diseases, indicating that the prevalence of lifestyle diseases is higher in AD patients with metabolic waist circumference than in all AD patients. In other words, 14.0% of all AD patients have metabolic syndrome [1].