Building-integrated photovoltaic (BIPV) systems offer environmental, economic, and energy benefits as they can generate electricity to power buildings and reduce heating and cooling loads. However, aged PV modules can easily ignite building insulation materials which might be combustible by creating high-temperature electric arcs. Given that, a novel PV façade that substitutes traditional exterior insulation materials of building facades, i.e., PV-integrated vacuum glazing (PV-VG) which is non-combustible, was proposed in this study. The thermal performances of PV-VG facades were investigated. Simulation results indicated that the thermal transmittance (U-value) of PV-VG façades, with a range from 0.23 to 0.61 W/(m2‧K), was approximately 46 ~ 80% lower than that of traditional concrete walls with traditional external insulation layers. As for the secondary heat transfer coefficient (g-value), compared to traditional insulation walls, the PV-VG insulated façade with crystalline silicon solar cells demonstrated a significant reduction in g-value, ranging from 36% to 77%. The influence of solar cell efficiency and concrete wall thickness on the U-value and g-value was subsequently analysed to optimize the thermal performance of the proposed facade. This study expands the design options for BIPV applications and provides guidelines for implementing PV-VG insulated facades.