Which Enzyme Uses What Tricks?
摘要
Enzymes bring about reaction rate acceleration through several tricks. Of the tricks used to bring down activation energy—some are entropic, and others are enthalpic in nature. Various tools are recruited and relied on by each enzyme in different proportions. All these are within the realm of simple physical and chemical explanations—the combined effect, however, is quite dramatic! While there is no common formula, each enzyme uses a combination of these tricks to achieve the objective (Fig. 5.1). Indeed—each enzyme is a biological experiment—just the same way evolutionary biologist Ernst Mayr described the evolution of each species.