Glucocorticoid toxicity index (GTI) is a useful degree proposed by using a meta-evaluation to assess the chance of systemic glucocorticoid exposure in sufferers laid low with inflammatory bowels illnesses (IBD). The GTI is computed based totally on cumulative glucocorticoid cumulative dose and duration within the first yr. After a prognosis of IBD. The contemporary take a look at objectives to check the literature to decide the utility of GTI in predicting the danger of glucocorticoid toxicity in IBD patients. A literature search turned into conducted to pick out research that evaluated the predictive price of GTI for toxicity in IBD patients. The retrieved articles suggest that cumulative glucocorticoid dose and length prior to three hundred and sixty five days of the diagnosis of IBD have been massive factors related to the prevalence of glucocorticoid toxicity in IBD sufferers. However, different next elements may additionally have an effect on the toxicity of glucocorticoid exposure in IBD patients, along with age, comorbidities, and genetic polymorphisms. Moreover, some of the research, the outcomes validated that GTI can be a valuable device for immunosuppressive management in IBD sufferers to be able to discover patients who're much more likely to revel in systemic toxicity at some stage in immunosuppressive treatment.