Advantages of Nanotechnology-Based Dosage Forms for Delivery of Herbal Drugs in Cancer

Cancer is also known as the malignant tumor, representing a significant global health challenge capable of affecting any part of the body (Siegel RL, Miller KD, Jemal A, CA Cancer J Clin 70:7–30, 2020). Metastasis is the formation of secondary malignant tumors in distant areas from the primary cancer location during the growth of cancer cells. Cancer can be cured by herbal drugs because they have various anticancer properties. The chemical composition of plant extract has an important and successful formulation. Formulation releases the active ingredients. Nanoparticles work as a vector. They enhance the drug’s solubility, mitigate the degradation process, diminish toxicity and mask undesirable taste, and manage the absorption of the active constituent as well as the biochemical response (Holmberg K, Shah DO, Schwager MJ (eds), Handbook of applied surface and colloid chemistry. Wiley, Goteborg, 2002). The implementation of nanotechnology and healthcare is known as nanomedicine. Nanomedicine shows significant potential in cancer, drug delivery systems, diagnostic tools, tissue-engineered constructs, implants, cardiovascular disease, musculoskeletal conditions, and neurodegenerative diseases. Liposomes, niosomes, microspheres, ethosomes, nanocapsules, polymeric nanoparticles, nanoemulsions, and phytosomes, are the best cutting-edge drug administration methods in phyto-formulation research and in cancer therapy. Cutting-edge drug administration methods are beneficial in cancer diagnosis and are used to increase the efficiency, and safety and enhance the convenience of drug delivery for patients. This chapter will explore the advantages of utilizing nanotechnology-encapsulated bioactive compounds for cancer treatment. Integrating plant drugs into the delivery system helps increase solubility and pharmacological activity, protection from toxicity, and improved distribution within tissue macrophages. NDDS for medicinal plants are used to optimize biological efficacy with new challenges.