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Vibrational spectroscopy, in the form of Raman and mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, enabling rapid screening, and can be employed for the diagnosis of multiple conditions at once and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point-of-care diagnosis by considering we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in critical care for rapid and early diagnosis of disease.

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Vibrational Spectroscopy for Rapid Bedside Medical Diagnosis

  • 会议论文

  • 发表日期：

    2025年

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  • Aneesh V. Veluthandath,
  • Waseem Ahmed,
  • Eleanor Osborne,
  • Ahilanandan Dushianthan,
  • Jens Madsen,
  • Howard W. Clark,
  • Anthony D. Postle,
  • James S. Wilkinson,
  • Ganapathy Senthil Murugan

摘要

Vibrational spectroscopy, in the form of Raman and mid-IR spectroscopies, is a powerful, label-free technique that can identify and quantify individual components of a complex chemical mixture which makes it ideal for analysis of biosamples. Vibrational spectroscopic measurements are quick, simple and easy to perform, enabling rapid screening, and can be employed for the diagnosis of multiple conditions at once and can be employed for the diagnosis of multiple conditions at once. We explore the use of vibrational spectroscopy for rapid point-of-care diagnosis by considering we study the diagnosis of neonatal respiratory distress syndrome of preterm babies. We are developing on-chip spectroscopy using low-cost and highly sensitive disposable chips. Together with machine learning, it will further simplify biomarker detection in critical care for rapid and early diagnosis of disease.