A study was conducted to assess the ground-level ozone (O3) pollution at an open-traffic site on National Highway 16 (NH-16) in Kharagpur, West Bengal, India. O3 concentration was measured using the Serinus 10 ozone analyzer, an instrument approved by the USEPA. Manual traffic count was made. Local meteorological information was obtained using a portable weather meter Kestrel 5500. Results revealed that elevated traffic levels during the morning and evening periods were associated with lower O3 levels, while the opposite trend was observed at noon. A good positive correlation (r = +0.84) was obtained between temperature and O3 levels, while a strong negative correlation (r = −0.87) was observed between traffic count and O3 concentrations. Furthermore, humidity emerged as the significant meteorological factor influencing the variations in O3 concentrations. The study findings highlight the need of understanding the intricate interplay of traffic volume, weather conditions and O3 chemistry at the traffic sites in order to effectively address air quality challenges and regulatory standards.