This study has been carried out to treat domestic wastewater through the combination of anaerobic treatment and deammonification in a pilot plant of 0.1 MLD in IIT Bhubaneswar campus. The pilot plant showed significant improvements in the removal of organic pollutants, particularly in terms of reducing chemical oxygen demand (COD) and total suspended solids (TSS), as well as effective nitrogen removal. The treated effluent from the pilot can be used for a applications such as gardening and toilet flushing. Furthermore, the biogas produced during the treatment process will be a significant fuel source, and the sludge produced during the procedure showed promise as nutrient-rich manure. The pilot plant, which included a UASB, demethanization, and MBBR-anammox processes, had specific objectives for wastewater treatment: organic matter removal, biogas production, nitrogen removal, and minimizing the environmental impact of wastewater discharge. Over a span of four months in operation, the integration of anaerobic treatment and deammonification technology notably improved removal efficiencies, achieving 93% for COD, 94% for TSS, 95% for TN, and 91% for TP. The sludge production from the plant amounted to 100 kg per year, serving as a valuable resource like fertilizer or soil amendment. Furthermore, the pilot plant yielded 0.07 MLD of treated water, representing the volume of clean and treated water obtained from the treatment process.