Radiation and Chemotherapy-Induced Cardiac Toxicity in Breast Cancer

Cardiovascular complications are one of the most common cause of morbidity and mortality in breast cancer patients and survivors. The clinical spectrum of the disease may vary from asymptomatic left ventricular dysfunction to valvular dysfunction, arrhythmias, conduction abnormalities, myocarditis, pericarditis and overt cardiac failure. Treatment guidelines remain the same as in general population; however, optimal sequencing of chemotherapy and radiotherapy and minimising chemoradiation dose can prevent or reduce the incidence of complications.