Management of Inflammatory Breast Cancer

Inflammatory breast cancer (IBC) is a rare subtype of locally advanced breast cancer (LABC). It is clinically defined by diffuse induration of the skin of the breast with a reddish appearance and oedema with or without an underlying mass. Inflammatory breast cancer is the most aggressive entity of breast cancer. The median overall survival among women is less than 4 years, even with multimodality treatment options. However, increased survival in recent years has been noted with the evolution of chemotherapeutic management, including hormone therapy, immunotherapy and targeted therapy. In this chapter, we shall discuss the presentation, investigations and management of inflammatory breast cancer.