Urinary tract infections (UTIs) in men are managed similarly to women, though no specific guidelines exist. First-line empiric antibiotics include trimethoprim-sulfamethoxazole, nitrofurantoin, or fosfomycin; fluoroquinolones are reserved for severe or suspected prostatic involvement. Beta-lactams may be used if other options are unsuitable. Routine follow-up urine cultures aren't needed if symptoms resolve, except in pregnancy or persistent hematuria. Referral is required for complicated UTIs, relapsing infections, suspected obstructions, or recurrent cases needing urologic evaluation. Imaging may be indicated in women with voiding issues or specific organisms like Proteus. Men with recurrent cystitis should be assessed for prostatic or structural abnormalities.