The adsorptive qualities of commercially available rice husk ash (RHA) were investigated for Safranin O dye. An investigation was conducted in batch mode to examine the impact of different factors, such as pH, initial dye concentration, temperature, contact time, adsorbent dose, and agitation speed (rpm), on the removal of dye. The state of adsorption equilibrium was reached after 40 min under optimal conditions of pH 7, 150 revolutions per minute, temperature of 303 Kelvin, and adsorbent dosage of 20 g per liter. The removal efficiency achieved was 99.27%. In addition, the equilibrium adsorption data was examined using isotherms such as Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich (D-R). The highest adsorption capacity was determined to be 39.21 mg/gm. The adsorption of Safranin onto RHA was positively affected by an increase in temperature. The adsorption data was best fitted by a second-order kinetic model, indicating chemisorption. The thermodynamic characteristics for the process are as follows: the change in entropy (∆S0) is 106.58 J/mol, the heat of adsorption (∆H0) is 27.86 kJ/mol, and the change in Gibb’s free energy (∆G0) is −2.96 kJ/mol at 293 K, −4.78 kJ/mol at 300 K, and −5.25 kJ/mol at 313 K. These values indicate that the adsorption process is endothermic, spontaneous, and favorable. Therefore, RHA has the potential to be utilized as an adsorbent to eliminate Safranin O dye.