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Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring functional molecules such as nucleic acids and proteins. However, their small size and heterogeneity present significant challenges for analysis, requiring new, standardized methods with high sensitivity and scalability. This chapter introduces cutting-edge technologies, focusing on optical measurements as a promising, non-destructive approach for enhancing EV analysis.

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High Dimensional Cytometry for Studying Heterogeneous Small Particles

  • 章节

  • 出版模式：

    开放获取

  • 发表日期：

    2025年

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  • Kazuki Hattori,
  • Yuichiro Iwamoto,
  • Ryosuke Kojima,
  • Yusuke Yoshioka,
  • Sadao Ota

摘要

Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring functional molecules such as nucleic acids and proteins. However, their small size and heterogeneity present significant challenges for analysis, requiring new, standardized methods with high sensitivity and scalability. This chapter introduces cutting-edge technologies, focusing on optical measurements as a promising, non-destructive approach for enhancing EV analysis.