Portfolio management has been a challenging task in the financial market for a long period. Several traditional and modern tools and techniques have been employed by researchers in this field in the last decades. Deep Reinforcement Learning (DRL) has been one of them which has produced excellent results for portfolio optimization. DRL offers a revolutionary approach to portfolio management by enabling dynamic, data-driven investment strategies. However, challenges such as sample efficiency, interpretability, and integration with existing systems hinder widespread adoption. This chapter explores these challenges and proposes future directions for DRL in portfolio management. Potential solutions like transfer learning and explainable artificial intelligence (XAI) have been discussed to improve sample efficiency and interpretability. Hybrid approaches that combine DRL with traditional methods and the development of robust risk management practices are explored. In addition, exciting future directions, including multi-agent learning, incorporating financial constraints and market microstructure, and the role of Explainable Reinforcement Learning (XRL) in socially responsible investing have also been explored. It has been observed that by addressing open questions concerning interpretability, ethical considerations, and regulatory frameworks, DRL can evolve into a powerful tool for investors, navigating complex markets and achieving their financial goals.