Among different forms of failures, fatigue is the primary mode of failure for composite materials. Repetitive stress and bending can lead to fatigue in structural composites. The fatigue properties of various composite materials differ from one another. Depending on the anticipated loading conditions and durability requirements of a given application, evaluating, and comparing fatigue characteristics assists in selecting the best composite. These applications include wind turbines, sporting products, the automobile, marine, and aerospace industries. Therefore, a comparative analysis of the fatigue performance of several textile-reinforced structural composites under flexural loading was performed in this study. The influence of different weave designs and weave architecture such as unidirectional (UD), two-dimensional (2D), and three-dimensional (3D) on fatigue behavior of composites was investigated. The residual strength and stiffness of the 3D woven composites were found to be highest during flexural deformation. Angle interlock fabric composite has the lowest stiffness degradation among 3D composites, while Satin fabric composite has the lowest stiffness degradation among 2D composites.