We present a numerical simulation of two-dimensional fluid flow through a plain and zigzag-shaped microchannel with water as a working fluid using smoothed particle hydrodynamics (SPH). The silicon channel walls are linked to a constant heat flux. We use the Tait equation of state (Eos) to calculate the pressure and a no-slip boundary condition to simulate the flow and heat transfer from the wall to the fluid. A reduction in flow velocity for a zigzag channel is observed for a fixed body force compared to a plain channel. Hence, a plain channel transfers more heat than a zigzag channel of the same physical length and width for a given constant body force. The effect of fluid velocity in heat transfer enhancement is studied.