The present work investigates the hydrothermal performances of MCHS incorporating dimple structures. Conical and cylindrical fins with dimples are used as a flow disruptive structure. To solve the governing equations, finite volume methodology (FVM) is considered. The results are presented using the parameter space of Po number, Nu number, and TP. A comparative study of different flow disruptive structures (conical fin, conical fin with dimple, cylindrical fin, and cylindrical fin with dimple) is done to find the superior MCHS design based on their TP values. It is observed that microfin improves the heat dissipation at the expense of pressure loss. The obtained results reveal that the conical fin configuration shows higher thermal characteristics when compared with the other configurations. The reduction in heat dissipation and pressure loss is observed while introducing the dimple inside the microchannel. Further, flow topology along with the streamlines is discussed to give the reasoning behind the different TP values of different design configurations.