Microneedle Patches for Soft Tissue Repair
摘要
Microneedle technology, a minimally invasive method, consists of tiny needles. Since its first research for skin in 1998, it is taking interest and enlarging its application through other tissues. Unfortunately, tissue loss or damage is one of the most important problems encountered in the clinic due to its significant negative impact on the patient's life and comfort as well as its cost to social security institutions. Microneedle arrays have proved their effectiveness for different tissues, which makes this technology a promising method for tissue healing. Especially, various advantages of microneedles such as high bioavailability and patient compliance as well as enabling long-term drug delivery for localized sites, easy adjustment of physical and chemical properties, and high drug loading capacity, will increase their usage alone or together with other systems in the future. In this chapter, we have addressed the soft tissue applications as well as providing a comprehensive review of microneedle technology.