Virtual Reality (VR) can be used to develop the simulation process for learning related to safety in the workplace. VR for simulated firefighting has several advantages, such as user safety factors, cheaper costs, and flexibility as a recurring learning medium. This study aims to design a simulation of fire extinguishers using VR and evaluate existing VR designs with usability testing. This study used the interaction design methods to design a simulation of the use of fire extinguishing equipment. The first stage of interaction design begins with identifying users’ needs through an interview process with five respondents. Based on the interview, there are six user requirement that can be used to develop a VR simulation. The second stage is to design alternative concepts and select selected concepts. Then, based on the selected concepts, the next stage is designing VR simulation. VR design was evaluated by involving several chemical engineering students who is undergoing practicum. The evaluation results show that the VR fire extinguisher has an efficiency level of 72%, an effectiveness level of 90%, and a Systems Usability Scale (SUS) score of 70.25, which means the VR simulation has good usability. Improvement recommendations were also given, namely by displaying how to use fire extinguishers more clearly and considering enough time for respondents to familiarize themselves with VR.