The European Climate Law aims to combat energy-inefficient buildings by prohibiting the rental of the most energy-consuming housing units. These restrictions, designed to address greenhouse gas emissions and energy conservation, are at the forefront of metropolitan concerns as part of their efforts toward ecological transition. MUST-B (integrated land Use Model—Transport application to the Urban area) is a Land Use Transport Interaction (LUTI) model that simulates households and workplaces location choices. It models and simulates the interaction of both the population of an urban area through their residential choices with activities and jobs, as well as the various transportation modes to meet daily mobility needs. This agent-based tool allows for understanding the complexity of an urban area based on individual behaviors giving rise to collective phenomena. In this article, our focus is on the “land use” component of the tool, specifically emphasizing the “multi-agent” aspect by developing two populations of agents in close interaction during the simulation: households and their residences. We also explore an example application related to a European regulation for the withdrawal of high-energy-consumption housing.