Microbial Inventions and Improvement in Industrial Bioprocess Development

Industrial microbiology deals with desired organisms that produce various industrially important products. It includes various aspects: growth of microorganisms and media formulation and optimization. Advancement in techniques resulted into production of a wide range of natural and non-natural products. Recently, researchers are developing techniques for strain improvements which enhance products and their characteristics. This chapter focuses on various aspects of growth of organisms including kinetics and product yields. As the media provides an environment for better growth, the development in media formulation and optimization with various methods is needed for enhancing the products. To increase product yields and to ensure consistent product quality, key issues of industrial fermentations, process optimization, and scale up are aimed at maintaining optimum and homogeneous reaction conditions minimizing microbial stress exposure and enhancing metabolic accuracy. Metabolic engineering and recombinant DNA technology are applied to generate engineered microbial strains to produce economically better products.