Spalling in concrete is a phenomenon when concrete shards detach and fall off from the structural members, leading to decrease in the load bearing capacity. Literatures have shown that pore pressure plays an important role in the occurrence of spalling in concrete members. This study discusses the variation in pore pressure when the structural member is subjected to non-uniform heating. The model is developed by coupling the principles of mechanics and thermodynamics to calculate the pore pressure inside normal strength concrete (NSC) member due to non-uniform heating. The results of the analytical model have been validated against the experimental results of uniform heating due to the unavailability of research considering non-uniform heating. Upon validation a reasonable agreement can be observed with the experimental results. Further, a case study of a possible non-uniform heating of structural element has been presented and pore pressure variation has been discussed. It is observed that pore pressure is different for different locations of the compartment with maximum at the start location of fire and minimum at the ends of the compartment. Further, this proposed model can be integrated into any existing modeling framework to study the macroscopic behavior of normal strength concrete members.